As reported in Yahoo, Deadspin, and here at Steroid Nation, former Jaguar QB Tim Couch, consulted with a Florida nutritionist for his NFL rehab comeback, who promotes the plant steroid laxogenin as anabolic for his company called Maxim Rejuvenation. (The write-up from the Maxim Website will be found after the jump). The claims are nonsense. The supplement Couch took might be weakly helpful for menopausal women. Likely any benefit Couch received at the clinic was from real steroids and HGH.
Yahoo has a video with Couch promoting Laxogen (go to Part 6). Good for strength, pumping up the metabolism, and hot flushes.
The Maxim website says this compound was discovered by an American scientist in 1996. Interesting because all publication are from Japan and China, the first in 1963: [Laxogenin, a new steroidal sapogenin isolated from Smilax sieboldi Miq.] Jpn J Pharmacol. 1963 May;83:557-8. Japanese. No abstract available. PMID: 14041495 [PubMed - indexed for MEDLINE].
There are 7 medically indexed publications on the compound. None look at the compound's anabolic use (Maxim claims found after the jump). You would think that the National Institutes of Health has a full bore research program on this compound for use in the Olympic Games. Not true. The last official paper on it was from the 'Shanghai Institute of Organic Chemistry' and discussed the synthesis of laxogenin from diosgenin.
This compound appears to be a plant steroid. Plant sterols might be interesting, but certainly untested for all the medical uses the Maxim website claims. There are some naturalists, with little scientific training, who make overblown claims for these plant steroid products.
The actual compound in this drug labeled Laxogenin, as analyzed by Dr. Don Catlin's lab at UCLA, was diosgenin (so much for truth in labeling). 'Disgenin' pulls up 347 references. This compound is called a sapogenin, and is found in yams. The molecule is being researched for a number of uses, however ALMOST NONE in human clinical trials.
Here is one clinical trial: Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 2001 Jun;4(2):144-50.
Menopausal women? Couch was taking a plant sterol for menopause? Hope it helps his hot flashes.
The other paper was looking at a sports drink called SPORT. There was no effect on performance parameters (reference found at the bottom)
This scheme sounds so Victor Conte and BALCO.
- Invent some bogus supplement as a covering ruse.
- Use anabolic steroids, anti-estrogens, and HGH to deliver real results.
- Market your snake-oil.
- Promote the product with athletes who obtained results from real anabolic drugs (Bonds, Romo, Marion Jones)
Fraud. The FDA. the FBI, and Gov't fraud agencies need to hunt down these renegades.
L- laxogenin, was discovered by a American scientist
in 1996. It was shown to possess an anabolic/androgenic ratio similar
to one of the most efficient anabolic substances, in particular Anavar
but without the side effects of liver toxicity or testing positive for
steroidal therapy. Athletes have found dramatic strength increases in
3-5 days, and muscle mass increases in 3-4 weeks. Muscle mass or fat
loss is only a function of caloric intake. If you are a male that is a
hard gainer or someone that is looking to put on extra lean muscle and
most important, keep it. This is the ONLY product EVER designed to do
this without steroidal influence. Product is great for drug testing and
does not test positive for steroids. Tests showed that protein
synthesis increased by over 200% , the key to lean muscle growth and
accelerated repair. Body fat reduction is one of the key components of
this molecule. When you restrict your calories you reduce body fat
In testing molecule has balance cortisol response which is the major cornerstone to healthy recovery and reduction of muscle wasting.
This product may be taken for post surgical injury repair. It regenerates the healing process by 10 fold with most surgeries. It is currently being tested for internal fistula repair, shoulder repair, knee surgery and general anabolic regeneration issues related to aging.
Aging is now viewed as a disease state. The catabolic, or destruction of mature healthy cells has been a problem for science throughout mankind.
This product is the closest product to repairing or regenerating
cellular decline. What does this mean in plain English? Basically, it
is the most important preventative, regenerative process in modern
This is a plant sterol from plants. Its purpose in the plant kingdom is to insure survival in inclement conditions. It does the same in the human body. The blood of the plant is only 1 molecule apart from the blood of a human. Recent science has concluded that plant sterols for age related conditions, such as, DNA repair and regeneration, are some of the most dynamic in modern medicine.
Recommendations for use: For Males 10mg, take 1 troche and let it melt in your mouth per day. Females take 2.5mg, troche 1 time per day. May have with or without food.
Remember: More isn’t better. This act’s as a signaling agent. Not a steroid.
Males may take 2 per day if training extremely hard and frequency.
Females not recommended to take more than 1 per day.
*Maxim recommends periodic diagnostic testing to determine the most advantageous scenerio for the individual.
Recommended Test Panels:
MHP, Male Hormone Panel: Androgen Pathway
ASI for Male and Female: Adrenal Panel
FHP, Cycling Female Hormone Panel
PHP-2 PeriMenopausal Hormone Panel
PHP-1 Menopausal Hormone Panel
Product is being currently tested for the reversal of the following diseases:
- Diabetes, all forms
- Injury repair, all types
- Knee injuries, specific
- Shoulder injuries, specific
- Children during adrenal development
- Cancer, MS, Lupus, etc.
Q & A
What are the two pathways through which Laxogenin works? RNA and Ribosome Assembly.
The literature given suggests that one pathway involves an increased rate in decoding RNA. But that's still too technical for me to fully grasp, and I can't find an explanation of the second pathway.
Basically, he is saying that by decoding RNA he is able to target the action of the molecular structure to stimulate a specific protein action. It is a catalyst for proper targeting function in the body. In this case, anabolic activity.
HGH therapy is a collection of 191 Amino Acids that are assembled and delivered by injection. If you take one step in reverse and figure out the sequencing equation of RNA, you can create the assembly and have the ribosomes create the assembly. The only thing you have to determine is how much to take to evoke the specified action. Which we did.
Messenger RNA tells the ribosome, a ribosome is a small, dense organelle in cells that assembles proteins and ribosomes build proteins from the genetic instructions held within a messenger RNA and assemble what kind of proteins to make and how much to crank out. They are basically the What is your experience with female weight loss?
Basically, all of our females that have tried this product say that they will never stop taking it. Better muscle tone, better , healthier appetite, better cellulite reduction and most important skin toning, smoothing effect.
What is your experience with male weight loss?
Remember, this product works synergistically with caloric intake. If you restrict your calorie intake and eat every 2.5 hours throughout the day and don’t miss your breakfast shake with Fiber and Fats for a complete meal, then you will lose fat without losing lean body mass! Most important and highly overlooked.
See eating secrets at Maxim Health System.
There are a couple of adjunct products that work great with the Laxogenin for both sex’s:
Males: ( it is recommended that hormone panels are completed prior to determine exact augmentation. MHP and ASI )
- Laxogenin: 1x per day in morning without food for at least 15 minutes for greatest absorption.
- DHEA: 25mg in am and 25mg at noon or eve.
- Tribulus: Special Tribulus 3 in am, 3 at noon.
- Alpha Lipoic 300: 1 in am, 1 at noon, 1 at eve.
- Energy Multi Vitamin: 1 in am, 1 at noon, 1 at eve.
- Zinc: 1 in am, 1 in pm. Note: some individuals may be sensitive and get a pain in the stomach. This is normal and take with food.
- EstroCleanse: 1 at bed for estrogen clearance maintenance.
- AminoPlex stimulant and non stimulant: 3x per day. To be used together. Read directions on bottle.
- Angstrom Minerals: Liquid. Take ½ oz . to 1 oz. 2x per day as needed. See Instructions.
- Enzymes: Most important to digest extra protein, fiber and fats. Take 1 with each meal.
Other Hybrid Products
- Xentropin: for added GH and recovery support. See instructions.
- Adrenal Booster: if needed see schedule
- Electrolyte Drink: During Workouts. Follow instructions.
- Pregnenolone: If needed see schedule